Biochemistry I

CHE 571

 Fall 2011


Time: MWF 11:00-11:50 
Instructor: Dr. Kimberly Bagley, SC 453, 878-5933, email: bagleyka@buffalostate.edu
Office Hours: MF 9:30-10:45 AM
Text: "Principles of Biochemistry"  (4th Ed.)  by Horton et. al.



Tentative Schedule


Date Topic Chapter
8/29 Introduction to Biochemistry 1
8/31 Properties of Water 2
9/2 pH and Buffers 2
PS 1
9/5 No Class
9/7 Amino Acids
9/9 Peptides 3
PS 2
9/12 Sequencing peptides 3
9/14 Protein Structure
9/16* Protein Structure 4
PS 3
9/19 Myoglobin  4
9/21 Hemoglobin  4
9/23 Enzyme Kinetics 5.0-5.5
9/26* Enzyme Inhibitors 5.7, 5.8
PS 4
9/28 Allosteric Enzymes 5.9
9/30 Regulation of Enzyme Kinetics 5.10
10/3 EXAM I (1-5.8)
10/5 Intro to Enzyme Mechanisms 6
10/7 Serine proteases 6
PS A
10/10 No Class

10/12 Other catalytic triads 6
10/15 Coenzymes, vitamins 7.0-7.6, 7.13, 7.14
PS B
10/17*Carbohydrates8
10/19 Carbohydrates 8
PS5
Haworth Structures
10/21 Carbohydrates 8
10/24* ATP as energy currency 10.5, 10.6
10/26 Lipids 9
PS6
10/28 Lipids 9
10/31 EXAM II (5.9, 5.10, 6,7,8,10)
11/2 Membranes 9
11/4 Membrane proteins 9
11/7 Fluid Mosaic Model 9
11/9 Nucleotides  19
PS7
11/11 DNA 19
11/14* DNA  19
11/16 Restriction endonucleases, DNA polymerases 20
11/18 DNA replication 20
11/21 DNA replication 20
11/23 No Class
11/25 No Class
11/28 Repair of Damaged DNA/ DNA recombination 20
11/30 Recombinant DNA technology 23.0-23.3
PS8
12/2* Restriction length polymorphisms 23.8-23.10
12/5 Site Directed Mutagenesis 23.12
12/7 The genetic code- an overview 22.1
12/15 EXAM  III (9:40- 11:30 am) Part I: (9,19, 20, 22, 23)

Part II: Comp.

*Quizzes Scheduled for these days (15 mins., 10 pts each).

PS: Related problem sets   for student practice (not collected).

Note: This is a tentative schedule. Exam dates and Quiz dates may change. All such changes will be announced during the regularly scheduled lecture periods.



GRADING:
 
Exams 
350 pts 
Quizzes (top 5 of 6 @ 10 pts each)
50 pts
Paper
50 pts 
TOTAL POSSIBLE POINTS                   450 pts


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