| Time: | MWF 11:00-11:50 | 
| Instructor: | Dr. Kimberly Bagley, SC 453, 878-5933, email: bagleyka@buffalostate.edu | 
| Office Hours: | MF 9:30-10:45 AM | 
| Text: | "Principles of Biochemistry" (4th Ed.) by Horton et. al. | 
Tentative Schedule
| Date | Topic | Chapter | 
| 8/29 | Introduction to Biochemistry | 1 | 
| 8/31 | Properties of Water | 2 | 
| 9/2 | pH and Buffers | 2
 PS 1  | 
| 9/5 | No Class | |
| 9/7 | Amino Acids | 3 | 
| 9/9 | Peptides | 3
 PS 2  | 
| 9/12 | Sequencing peptides | 3 | 
| 9/14 | Protein Structure | 4 | 
| 9/16* | Protein Structure | 4
 PS 3  | 
| 9/19 | Myoglobin | 4 | 
| 9/21 | Hemoglobin | 4 | 
| 9/23 | Enzyme Kinetics | 5.0-5.5 | 
| 9/26* | Enzyme Inhibitors | 5.7, 5.8
 PS 4  | 
| 9/28 | Allosteric Enzymes | 5.9 | 
| 9/30 | Regulation of Enzyme Kinetics | 5.10 | 
| 10/3 | EXAM I | (1-5.8) | 
| 10/5 | Intro to Enzyme Mechanisms | 6 | 
| 10/7 | Serine proteases | 6 PS A  | 
| 10/10 | No Class | 
|
| 10/12 | Other catalytic triads | 6 | 
| 10/14 | Coenzymes, vitamins | 7.0-7.6, 7.13, 7.14 PS B  | 
| 10/17* | Carbohydrates | 8
 | 
| 10/19 | Carbohydrates | 8 PS5 Haworth Structures  | 
| 10/21 | Carbohydrates | 8 | 
| 10/24* | ATP as energy currency | 10.5, 10.6 | 
| 10/26 | Lipids | 9
 PS6  | 
| 10/28 | Lipids | 9 | 
| 10/31 | EXAM II | (5.9, 5.10, 6,7,8,10) | 
| 11/2 | Membranes | 9 | 
| 11/4 | Membrane proteins | 9 | 
| 11/7 | Fluid Mosaic Model | 9 | 
| 11/9 | Nucleotides | 19
 PS7  | 
| 11/11 | DNA | 19 | 
| 11/14* | DNA | 19 | 
| 11/16 | Restriction endonucleases, DNA polymerases | 20 | 
| 11/18 | DNA replication | 20 | 
| 11/21 | DNA replication | 20 | 
| 11/23 | No Class | |
| 11/25 | No Class | |
| 11/28 | Repair of Damaged DNA/ DNA recombination | 20 | 
| 11/30 | Recombinant DNA technology | 23.0-23.3
 PS8  | 
| 12/2* | Restriction length polymorphisms | 23.8-23.10 | 
| 12/5 | Site Directed Mutagenesis | 23.12 | 
| 12/7 | The genetic code- an overview | 22.1 | 
| 12/15 | EXAM III (9:40- 11:30 am) | Part I: (9,19, 20, 22, 23)
 Part II: Comp.  | 
*Quizzes Scheduled for these days (15 mins., 10 pts each).
PS: Related problem sets for student practice (not collected).
Note: This is a tentative schedule. Exam dates and Quiz dates may change. All such changes will be announced during the regularly scheduled lecture periods.
| Exams | 
 350 pts  
 | 
| Quizzes (top 5 of 6 @ 10 pts each) | 
 50 pts 
 | 
| TOTAL POSSIBLE POINTS | 
 400 pts  
 | 
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