Solution to PS 1 #11
Yes, once the U2 snRNP binds at the branch site it will occlude the
U5 snRNP from binding at the 3' splice site and interfere with spicing.
Also, the deletion will have moved a large part of the pyrimidine
stretch required for binding to the 3'splice site. Both of these
will prevent proper mRNA processing and the aberrent RNA will not
be properly translated.
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