Solution to PS 4 #8


The inner mitochondrial membrane is impermeable to NADH.  The reducing equivalents are transferred across the mitochondrial membrane indirectly.  They are tranferred to oxaloacetate (which becomes labeled with 3H)  in the cytosol.  Malate is then formed (labeled with 3H) which is transported into the matrix, and then mitochondrial NAD+ is reduce to NADH.


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