CHE 300
Spring 2005
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S. Aldridge, Cambridge University Press |
| Date | Material | Reading* |
|---|---|---|
| 1/24 | How Drugs Work | Ch. 1 |
| 1/26 | Protein Structure | Ch. 1
HW 1-15 pts** (due 2/4) |
| 1/28 | Steriospecificity and Drugs | Ch 1 |
| 1/31 | Fate of Drugs in the Body | Ch 1 |
| 2/2 | First Pass Effect/ Bioavailability | Ch 1 |
| 2/4 | Side Effects/Drug-drug Interactions | Ch 1 |
| 2/7 | Routes of Administration | Ch 1 |
| 2/9 | The Placenta/ The Blood-Brain Barrier | Ch 1
HW 2-10 pts (due 2/ 18) |
| 2/11 | Drugs from
Nature
Movie: 20th Century Medicine Man |
Ch. 2 |
| 2/14 | Drug Development | Ch 2 |
| 2/16 | Rational Design/ Combinatorial Techniques | Ch 2 |
| 2/18 | Drug Regulation and Testing | Ch 2
HW 3-15 pts (due 3/2) |
| 2/21 | No Class | |
| 2/23 | The Placebo
Effect/ Double Blind Trials
Supplementary Material- Lecture #13 |
Ch 2 |
| 2/25 | Naming Drugs/Generic Drugs/ OTC's | |
| 2/28 | EXAM I (1/24 - 2/23) | |
| 3/2 | Movie- The Coming Plague | HW
4-15 pts
(due 3/9) |
| 3/4 | Antibiotics- Sulfa drugs | Ch. 3 |
| 3/7 | Penicillins and Cephalosporins | Ch. 3 |
| 3/9 | DNA and Protein Synthesis | Ch. 3 |
| 3/11 | Tetracycline, Erythromycin, Streptomycin. | Ch. 3 |
| 3/14 | Viruses | Ch. 3
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| 3/16 | Antivirals | Ch. 3
HW 5- 10 pts (due 3/25) |
| 3/18 | The Immune System | Ch. 3 |
| 3/21 | Movie- Polio Vaccine | |
| 3/23 | Vaccines | Ch. 3 |
| 3/25 | Drugs at
the Synapse
Supplementary Material- Lecture #27 Exam II (2/25-3/23) (Take-Home Exam due 4/6) |
Ch. 8 |
| 3/28 | Spring Break | |
| 3/30 | Spring Break | |
| 4/1 | Spring Break | |
| 4/4 | Drugs to Treat Depresssion | Ch. 8
HW 6- 10 pts (due 4/11) |
| 4/6 | Drugs to treat anxiety/ The GABA receptor | Ch. 8, 9 |
| 4/8 | Drugs Acting on the Sympathetic Nervous System | Ch. 8 |
| 4/11 | The Opiates | Ch. 6 |
| 4/13 | The Opioids | Ch. 6 |
| 4/15 | NSAID's | Ch. 6
HW 7- 15 pts (due 4/22) |
| 4/18 | COX-1 and
COX-2 inhibitors
Supplementary Material- Lecture #34 |
Ch. 6 |
| 4/20 | Acetaminophen
vs. Aspirin
Supplementary Material- Lecture #35 |
Ch. 6 |
| 4/22 | Antihistamines | |
| 4/25 | Drugs for treating GERD | |
| 4/27 | Cholesterol, Artherosclerosis, and the Statins | Ch. 5
HW 8- 10 pts (due 5/4) |
| 4/29 | Drugs for Cardiovascular Disease: Antihypertensives | Ch. 5 |
| 5/2 | EXAM III (3/25-4/29) | |
| 5/4 | Review | |
| 5/11 | FINAL
EXAM (Cummulative)
(7:40-9:30 AM) |
*Reading from "Magic Molecules- How Drugs Work" by S. Aldridge
**Homework assignments.