Solution to PS 3 #3
1) Backbone -bonds involving the C=O and N-H groups of the polypeptide
chain.
2) Side chain -bonds involving any possible H-bond donor (N-H
of R group in His, Arg, Lys, etc.; OH's in Asp, Ser, etc.) or acceptors
on the side chain (O's on side chains: C=O in Asp, Glu; OH in Tyr,
etc.; Some N's in Side chains)
3) Hydrophobic interactions involving non-polar groups in a protein
(many possiilities).
4) Electrostatic interactions involving charged groups; Example:
at pH 7 Asp carries a neg. charge and Lys carries a pos. charge
so a salt brige can form between the two side Chains at pH 7.
5) Metal ligation involving coordination between side chains
atoms (often S, O, or N) and a metal ion. [Asp, Glu, Cys, Tyr, His,
Met, Lys are commonly found as ligands to metal ions.]
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